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New PlasticsFatE Video: Rethinking How We Assess the Health Risks of Micro- and Nanoplastics

What do tiny plastic particles do to the human body? And how should we respond?


In our latest PlasticsFatE video, now live on YouTube, we break down our science-based policy recommendations for managing the risks of micro- and nanoplastics (MNPs)—and what needs to change in how we understand, monitor, and regulate them.


Our lab studies tested a wide variety of MNPs on human cell models representing the lungs, gut, and immune system. The results? No immediate signs of cell death—but clear signs that these particles disrupt cell function in subtle, significant ways.


Cells altered how they produced mucus, immune signals, and even the surfactants that keep our lungs working properly.


This means we need to look beyond traditional toxicity tests. It’s not just about whether cells survive—it’s about how they behave.


Even more concerning: the strongest effects often came not from the plastics themselves, but from what they carried—harmful chemicals or pathogens hitching a ride.


Exposure routes
Exposure routes


Possible impacts on human health
Possible impacts on human health

That’s why our policy work is calling for a shift in risk assessment and regulatory focus:

  • Use new “functional biomarkers” to detect early cellular disruption

  • Set legal safety limits for MNPs in air, food, and water

  • Establish global testing standards and transparent data sharing

  • Design safer plastics through informed industry practices

  • Educate consumers on practical steps to reduce exposure


From food chain monitoring to long-term health studies, the road ahead requires cooperation across science, policy, and industry. Our video explains where we go from here—and how you can be part of the solution.


🎥 Watch now on YouTube


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